Adipocyte-specific expression of C-type natriuretic peptide suppresses lipid metabolism and adipocyte hypertrophy in adipose tissues in mice fed high-fat diet

C-type natriuretic peptide (CNP) is expressed in diverse tissues, including adipose and endothelium, and exerts its effects by binding to and activating its receptor, guanylyl cyclase B. Natriuretic peptides regulate intracellular cGMP and phosphorylated vasodilator-stimulated phosphoprotein (VASP)....

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Publicado en:Sci Rep
Autores principales: Bae, Cho-Rong, Hino, Jun, Hosoda, Hiroshi, Son, Cheol, Makino, Hisashi, Tokudome, Takeshi, Tomita, Tsutomu, Hosoda, Kiminori, Miyazato, Mikiya, Kangawa, Kenji
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2018
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5794866/
https://ncbi.nlm.nih.gov/pubmed/29391544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-20469-z
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