C-type natriuretic peptide ameliorates pulmonary fibrosis by acting on lung fibroblasts in mice

BACKGROUND: Pulmonary fibrosis has high rates of mortality and morbidity; however, no effective pharmacological therapy has been established. C-type natriuretic peptide (CNP), a member of the natriuretic peptide family, selectively binds to the transmembrane guanylyl cyclase (GC)-B receptor and exer...

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Detalhes bibliográficos
Publicado no:Respir Res
Main Authors: Kimura, Toru, Nojiri, Takashi, Hino, Jun, Hosoda, Hiroshi, Miura, Koichi, Shintani, Yasushi, Inoue, Masayoshi, Zenitani, Masahiro, Takabatake, Hiroyuki, Miyazato, Mikiya, Okumura, Meinoshin, Kangawa, Kenji
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4761143/
https://ncbi.nlm.nih.gov/pubmed/26895702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-016-0335-6
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