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Adipocyte-specific expression of C-type natriuretic peptide suppresses lipid metabolism and adipocyte hypertrophy in adipose tissues in mice fed high-fat diet

C-type natriuretic peptide (CNP) is expressed in diverse tissues, including adipose and endothelium, and exerts its effects by binding to and activating its receptor, guanylyl cyclase B. Natriuretic peptides regulate intracellular cGMP and phosphorylated vasodilator-stimulated phosphoprotein (VASP)....

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Bae, Cho-Rong, Hino, Jun, Hosoda, Hiroshi, Son, Cheol, Makino, Hisashi, Tokudome, Takeshi, Tomita, Tsutomu, Hosoda, Kiminori, Miyazato, Mikiya, Kangawa, Kenji
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5794866/
https://ncbi.nlm.nih.gov/pubmed/29391544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-20469-z
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