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Model-based optimization of G-CSF treatment during cytotoxic chemotherapy

PURPOSE: Although G-CSF is widely used to prevent or ameliorate leukopenia during cytotoxic chemotherapies, its optimal use is still under debate and depends on many therapy parameters such as dosing and timing of cytotoxic drugs and G-CSF, G-CSF pharmaceuticals used and individual risk factors of p...

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Bibliographische Detailangaben
Veröffentlicht in:J Cancer Res Clin Oncol
Hauptverfasser: Schirm, Sibylle, Engel, Christoph, Loibl, Sibylle, Loeffler, Markus, Scholz, Markus
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Berlin Heidelberg 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5794835/
https://ncbi.nlm.nih.gov/pubmed/29103159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00432-017-2540-1
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