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Modelling chemotherapy effects on granulopoiesis

BACKGROUND: Although the growth-factor G-CSF is widely used to prevent granulotoxic side effects of cytotoxic chemotherapies, its optimal use is still unknown since treatment outcome depends on many parameters such as dosing and timing of chemotherapies, pharmaceutical derivative of G-CSF used and i...

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Publicat a:BMC Syst Biol
Autors principals: Schirm, Sibylle, Engel, Christoph, Loeffler, Markus, Scholz, Markus
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4302124/
https://ncbi.nlm.nih.gov/pubmed/25539928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-014-0138-7
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