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Modelling chemotherapy effects on granulopoiesis

BACKGROUND: Although the growth-factor G-CSF is widely used to prevent granulotoxic side effects of cytotoxic chemotherapies, its optimal use is still unknown since treatment outcome depends on many parameters such as dosing and timing of chemotherapies, pharmaceutical derivative of G-CSF used and i...

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Publicado en:BMC Syst Biol
Autores principales: Schirm, Sibylle, Engel, Christoph, Loeffler, Markus, Scholz, Markus
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4302124/
https://ncbi.nlm.nih.gov/pubmed/25539928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-014-0138-7
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