Genotyping and mRNA profiling reveal actionable molecular targets in biliary tract cancers

Biliary tract cancer (BTC) represents a heterogeneous disease with dismal outcome. Herein, we examined genotype and angiogenesis features in BTC. We applied genotyping (Sanger, qPCR, 101-gene panel NGS), mRNA relative quantification methods, and β-catenin immunohistochemistry in 84 FFPE BTC (55 gall...

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Dettagli Bibliografici
Pubblicato in:Am J Cancer Res
Autori principali: Papadopoulou, Kyriaki, Murray, Samuel, Manousou, Kyriaki, Tikas, Ioannis, Dervenis, Christos, Sgouros, Joseph, Rontogianni, Dimitra, Lakis, Sotirios, Bobos, Mattheos, Poulios, Christos, Pervana, Stavroula, Lazaridis, Georgios, Fountzilas, George, Kotoula, Vassiliki
Natura: Artigo
Lingua:Inglês
Pubblicazione: e-Century Publishing Corporation 2018
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5794717/
https://ncbi.nlm.nih.gov/pubmed/29416916
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