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Calcimimetic R568 inhibits tetrodotoxin-sensitive colonic electrolyte secretion and reduces c-fos expression in myenteric neurons

AIMS: Calcium-sensing receptor (CaSR) is expressed on neurons of both submucosal and myenteric plexuses of the enteric nervous system (ENS) and the CaSR agonist R568 inhibited Cl(−) secretion in intestine. The purpose of this study was to localize the primary site of action of R568 in the ENS and to...

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Pubblicato in:Life Sci
Autori principali: Sun, Xiangrong, Tang, Lieqi, Winesett, Steven, Chang, Wenhan, Cheng, Sam Xianjun
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5794538/
https://ncbi.nlm.nih.gov/pubmed/29247746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.lfs.2017.12.019
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