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Calcimimetic acts on enteric neuronal CaSR to reverse cholera toxin-induced intestinal electrolyte secretion

Treatment of acute secretory diarrheal illnesses remains a global challenge. Enterotoxins produce secretion through direct epithelial action and indirectly by activating enteric nervous system (ENS). Using a microperfused colonic crypt technique, we have previously shown that R568, a calcimimetic th...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Tang, Lieqi, Jiang, Lingli, McIntyre, Megan E., Petrova, Ekaterina, Cheng, Sam X.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5959902/
https://ncbi.nlm.nih.gov/pubmed/29777154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-26171-4
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