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Loss of NRF2 function exacerbates the pathophysiology of sickle cell disease in a transgenic mouse model
The basic leucine zipper transcription factor nuclear factor (erythroid-derived 2)-like 2 (NRF2) plays a critical role in the cellular antioxidant response under oxidative stress conditions. In this study, we investigated the role of NRF2 in fetal hemoglobin expression and the pathophysiology of sic...
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| Publicado no: | Blood |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5794503/ https://ncbi.nlm.nih.gov/pubmed/29255069 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-10-810531 |
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