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Nrf2 activation in myeloid cells and endothelial cells differentially mitigates sickle cell disease pathology in mice
Sickle cell disease (SCD) is caused by a monogenic mutation of the β-globin gene and affects millions of people worldwide. SCD is associated with sustained hemolytic anemia, vasoocclusion, ischemia-reperfusion injury, oxidative tissue damage, inflammatory cell activation, and systemic endothelial dy...
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| Publicado no: | Blood Adv |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6482351/ https://ncbi.nlm.nih.gov/pubmed/31015205 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2018017574 |
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