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Diacylglycerol kinase α deficiency alters inflammation markers in adipose tissue in response to a high-fat diet

Conversion of diacylglycerol to phosphatidic acid is mediated by diacylglycerol kinases (DGKs), with DGKα specifically linked to adaptive immune responses. We determined the role of DGKα in obesity and inflammatory responses to a high-fat diet (HFD). DGKα KO and WT littermates were either a) chow-fe...

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Dettagli Bibliografici
Pubblicato in:J Lipid Res
Autori principali: Nascimento, Emmani B. M., Mannerås-Holm, Louise, Chibalin, Alexander V., Björnholm, Marie, Zierath, Juleen R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Biochemistry and Molecular Biology 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5794422/
https://ncbi.nlm.nih.gov/pubmed/29233919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M079517
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