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Diacylglycerol kinase α deficiency alters inflammation markers in adipose tissue in response to a high-fat diet

Conversion of diacylglycerol to phosphatidic acid is mediated by diacylglycerol kinases (DGKs), with DGKα specifically linked to adaptive immune responses. We determined the role of DGKα in obesity and inflammatory responses to a high-fat diet (HFD). DGKα KO and WT littermates were either a) chow-fe...

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Bibliografiske detaljer
Udgivet i:J Lipid Res
Main Authors: Nascimento, Emmani B. M., Mannerås-Holm, Louise, Chibalin, Alexander V., Björnholm, Marie, Zierath, Juleen R.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Biochemistry and Molecular Biology 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5794422/
https://ncbi.nlm.nih.gov/pubmed/29233919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M079517
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