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Conversion of adult endothelium to immunocompetent haematopoietic stem cells
Developmental pathways that orchestrate the fleeting transition of endothelial cells into haematopoietic stem cells remain undefined. Here we demonstrate a tractable approach for fully converting adult mouse endothelial cells to haematopoietic stem cells (rEC-HSCs) through transient expression of ge...
Shranjeno v:
| izdano v: | Nature |
|---|---|
| Main Authors: | , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2017
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5794215/ https://ncbi.nlm.nih.gov/pubmed/28514438 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature22326 |
| Oznake: |
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