Conversion of adult endothelium to immunocompetent haematopoietic stem cells

Developmental pathways that orchestrate the fleeting transition of endothelial cells into haematopoietic stem cells remain undefined. Here we demonstrate a tractable approach for fully converting adult mouse endothelial cells to haematopoietic stem cells (rEC-HSCs) through transient expression of ge...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nature
Egile Nagusiak: Lis, Raphael, Karrasch, Charles C., Poulos, Michael G., Kunar, Balvir, Redmond, David, Barcia Duran, Jose G., Badwe, Chaitanya R., Schachterle, Will, Ginsberg, Michael, Xiang, Jenny, Tabrizi, Arash Rafii, Shido, Koji, Rosenwaks, Zev, Elemento, Olivier, Speck, Nancy, Butler, Jason M., Scandura, Joseph M., Rafii, Shahin
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2017
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5794215/
https://ncbi.nlm.nih.gov/pubmed/28514438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature22326
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