Conversion of adult endothelium to immunocompetent haematopoietic stem cells

Developmental pathways that orchestrate the fleeting transition of endothelial cells into haematopoietic stem cells remain undefined. Here we demonstrate a tractable approach for fully converting adult mouse endothelial cells to haematopoietic stem cells (rEC-HSCs) through transient expression of ge...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Nature
Main Authors: Lis, Raphael, Karrasch, Charles C., Poulos, Michael G., Kunar, Balvir, Redmond, David, Barcia Duran, Jose G., Badwe, Chaitanya R., Schachterle, Will, Ginsberg, Michael, Xiang, Jenny, Tabrizi, Arash Rafii, Shido, Koji, Rosenwaks, Zev, Elemento, Olivier, Speck, Nancy, Butler, Jason M., Scandura, Joseph M., Rafii, Shahin
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5794215/
https://ncbi.nlm.nih.gov/pubmed/28514438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature22326
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki