Endothelial jagged-2 sustains hematopoietic stem and progenitor reconstitution after myelosuppression

Angiocrine factors, such as Notch ligands, supplied by the specialized endothelial cells (ECs) within the bone marrow and splenic vascular niche play an essential role in modulating the physiology of adult hematopoietic stem and progenitor cells (HSPCs). However, the relative contribution of various...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Guo, Peipei, Poulos, Michael G., Palikuqi, Brisa, Badwe, Chaitanya R., Lis, Raphael, Kunar, Balvir, Ding, Bi-Sen, Rabbany, Sina Y., Shido, Koji, Butler, Jason M., Rafii, Shahin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5707154/
https://ncbi.nlm.nih.gov/pubmed/29058691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI92309
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