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Endothelial jagged-2 sustains hematopoietic stem and progenitor reconstitution after myelosuppression

Angiocrine factors, such as Notch ligands, supplied by the specialized endothelial cells (ECs) within the bone marrow and splenic vascular niche play an essential role in modulating the physiology of adult hematopoietic stem and progenitor cells (HSPCs). However, the relative contribution of various...

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Bibliographische Detailangaben
Veröffentlicht in:J Clin Invest
Hauptverfasser: Guo, Peipei, Poulos, Michael G., Palikuqi, Brisa, Badwe, Chaitanya R., Lis, Raphael, Kunar, Balvir, Ding, Bi-Sen, Rabbany, Sina Y., Shido, Koji, Butler, Jason M., Rafii, Shahin
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5707154/
https://ncbi.nlm.nih.gov/pubmed/29058691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI92309
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