Endothelial jagged-2 sustains hematopoietic stem and progenitor reconstitution after myelosuppression

Angiocrine factors, such as Notch ligands, supplied by the specialized endothelial cells (ECs) within the bone marrow and splenic vascular niche play an essential role in modulating the physiology of adult hematopoietic stem and progenitor cells (HSPCs). However, the relative contribution of various...

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Dades bibliogràfiques
Publicat a:J Clin Invest
Autors principals: Guo, Peipei, Poulos, Michael G., Palikuqi, Brisa, Badwe, Chaitanya R., Lis, Raphael, Kunar, Balvir, Ding, Bi-Sen, Rabbany, Sina Y., Shido, Koji, Butler, Jason M., Rafii, Shahin
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5707154/
https://ncbi.nlm.nih.gov/pubmed/29058691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI92309
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