Decreased production of class-switched antibodies in neonatal B cells is associated with increased expression of miR-181b

The increased susceptibility to infections of neonates is caused by an immaturity of the immune system as a result of both qualitative and quantitative differences between neonatal and adult immune cells. With respect to B cells, neonatal antibody responses are known to be decreased. Accountable for...

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Veröffentlicht in:PLoS One
Hauptverfasser: Glaesener, Stephanie, Jaenke, Christine, Habener, Anika, Geffers, Robert, Hagendorff, Petra, Witzlau, Katrin, Imelmann, Esther, Krueger, Andreas, Meyer-Bahlburg, Almut
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2018
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5794184/
https://ncbi.nlm.nih.gov/pubmed/29389970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0192230
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