Decreased production of class-switched antibodies in neonatal B cells is associated with increased expression of miR-181b

The increased susceptibility to infections of neonates is caused by an immaturity of the immune system as a result of both qualitative and quantitative differences between neonatal and adult immune cells. With respect to B cells, neonatal antibody responses are known to be decreased. Accountable for...

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Publicado en:PLoS One
Autores principales: Glaesener, Stephanie, Jaenke, Christine, Habener, Anika, Geffers, Robert, Hagendorff, Petra, Witzlau, Katrin, Imelmann, Esther, Krueger, Andreas, Meyer-Bahlburg, Almut
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2018
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5794184/
https://ncbi.nlm.nih.gov/pubmed/29389970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0192230
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