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Effective regeneration of dystrophic muscle using autologous iPSC-derived progenitors with CRISPR-Cas9 mediated precise correction
Duchenne muscular dystrophy (DMD) is a lethal muscle wasting disease caused by a lack of dystrophin, which eventually leads to apoptosis of muscle cells and impaired muscle contractility. Clustered Regularly Interspaced Short Palindromic Repeats/ CRISPR associated protein 9 (CRISPR/Cas9) gene editin...
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| Pubblicato in: | Med Hypotheses |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5793935/ https://ncbi.nlm.nih.gov/pubmed/29317080 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mehy.2017.11.009 |
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