Mapping protein interactions of sodium channel Na(V)1.7 using epitope‐tagged gene‐targeted mice

The voltage‐gated sodium channel Na(V)1.7 plays a critical role in pain pathways. We generated an epitope‐tagged Na(V)1.7 mouse that showed normal pain behaviours to identify channel‐interacting proteins. Analysis of Na(V)1.7 complexes affinity‐purified under native conditions by mass spectrometry r...

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Detaylı Bibliyografya
Yayımlandı:EMBO J
Asıl Yazarlar: Kanellopoulos, Alexandros H, Koenig, Jennifer, Huang, Honglei, Pyrski, Martina, Millet, Queensta, Lolignier, Stéphane, Morohashi, Toru, Gossage, Samuel J, Jay, Maude, Linley, John E, Baskozos, Georgios, Kessler, Benedikt M, Cox, James J, Dolphin, Annette C, Zufall, Frank, Wood, John N, Zhao, Jing
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2018
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Resource
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5793798/
https://ncbi.nlm.nih.gov/pubmed/29335280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201796692
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