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Functional Defects From Endocrine Disease–Associated Mutations in HLXB9 and Its Interacting Partner, NONO

The insulin-secreting pancreatic neuroendocrine tumors, insulinomas, characterized by increased pancreatic islet β-cell proliferation, express the phosphorylated isoform of the β-cell differentiation factor HLXB9 that interacts with NONO/p54(NRB), a survival factor. Interestingly, two different homo...

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Detalhes bibliográficos
Publicado no:Endocrinology
Main Authors: Kharade, Sampada S., Parekh, Vaishali I., Agarwal, Sunita K.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5793795/
https://ncbi.nlm.nih.gov/pubmed/29309627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2017-03155
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