GSK-3β Protein Phosphorylates and Stabilizes HLXB9 Protein in Insulinoma Cells to Form a Targetable Mechanism of Controlling Insulinoma Cell Proliferation

Insulinomas (pancreatic islet β cell tumors) are the most common type of functioning pancreatic neuroendocrine tumors that occur sporadically or as a part of the MEN1 syndrome that is caused by germ line mutations in MEN1. Tissue-specific tumor predisposition from germ line mutations in ubiquitously...

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מידע ביבליוגרפי
Main Authors: Desai, Shruti S., Modali, Sita D., Parekh, Vaishali I., Kebebew, Electron, Agarwal, Sunita K.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2014
נושאים:
Molecular Bases of Disease
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3937616/
https://ncbi.nlm.nih.gov/pubmed/24425879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.533612
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