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Prion-Like Characteristics of Polyglutamine-Containing Proteins

Transmissible spongiform encephalopathies are infectious neurodegenerative diseases caused by the conversion of prion protein (PrP) into a self-replicating conformation that spreads via templated conversion of natively folded PrP molecules within or between cells. Recent studies provide compelling e...

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Detalhes bibliográficos
Publicado no:Cold Spring Harb Perspect Med
Main Authors: Pearce, Margaret M.P., Kopito, Ron R.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5793740/
https://ncbi.nlm.nih.gov/pubmed/28096245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a024257
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