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Engraftment of Human Pluripotent Stem Cell-derived Progenitors in the Inner Ear of Prenatal Mice

There is, at present, no curative treatment for genetic hearing loss. We have previously reported that transuterine gene transfer of wild type CONNEXIN30 (CX30) genes into otocysts in CX30-deleted mice could restore hearing. Cell transplantation therapy might be another therapeutic option, although...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Takeda, Hiroki, Hosoya, Makoto, Fujioka, Masato, Saegusa, Chika, Saeki, Tsubasa, Miwa, Toru, Okano, Hideyuki, Minoda, Ryosei
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5792596/
https://ncbi.nlm.nih.gov/pubmed/29386634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-20277-5
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