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Engraftment of Human Pluripotent Stem Cell-derived Progenitors in the Inner Ear of Prenatal Mice

There is, at present, no curative treatment for genetic hearing loss. We have previously reported that transuterine gene transfer of wild type CONNEXIN30 (CX30) genes into otocysts in CX30-deleted mice could restore hearing. Cell transplantation therapy might be another therapeutic option, although...

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Vydáno v:Sci Rep
Hlavní autoři: Takeda, Hiroki, Hosoya, Makoto, Fujioka, Masato, Saegusa, Chika, Saeki, Tsubasa, Miwa, Toru, Okano, Hideyuki, Minoda, Ryosei
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5792596/
https://ncbi.nlm.nih.gov/pubmed/29386634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-20277-5
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