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Engraftment of Human Pluripotent Stem Cell-derived Progenitors in the Inner Ear of Prenatal Mice

There is, at present, no curative treatment for genetic hearing loss. We have previously reported that transuterine gene transfer of wild type CONNEXIN30 (CX30) genes into otocysts in CX30-deleted mice could restore hearing. Cell transplantation therapy might be another therapeutic option, although...

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Foilsithe in:Sci Rep
Main Authors: Takeda, Hiroki, Hosoya, Makoto, Fujioka, Masato, Saegusa, Chika, Saeki, Tsubasa, Miwa, Toru, Okano, Hideyuki, Minoda, Ryosei
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group UK 2018
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5792596/
https://ncbi.nlm.nih.gov/pubmed/29386634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-20277-5
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