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MET or NRAS amplification is an acquired resistance mechanism to the third-generation EGFR inhibitor naquotinib
As a third-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI), osimeritnib is the standard treatment for patients with non-small cell lung cancer harboring the EGFR T790M mutation; however, acquired resistance inevitably develops. Therefore, a next-generation treatmen...
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| 發表在: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group UK
2018
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5792548/ https://ncbi.nlm.nih.gov/pubmed/29386539 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-20326-z |
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