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Decoding the Mechanism of Intramolecular Cu-Directed Hydroxylation of sp(3) C−H Bonds

The use of copper in directed C−H oxidation has been relatively underexplored. In a seminal example, Schönecker showed that copper and O(2) promoted the hydroxylation of steroid-containing ligands. Recently, Baran (J. Am. Chem. Soc. 2015, 137, 13776) improved the reaction conditions to oxidize simil...

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Detalhes bibliográficos
Publicado no:J Org Chem
Main Authors: Trammell, Rachel, See, Yi Yang, Herrmann, Aaron T., Xie, Nan, Díaz, Daniel E., Siegler, Maxime. A., Baran, Phil S., Garcia-Bosch, Isaac
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5792191/
https://ncbi.nlm.nih.gov/pubmed/28654755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.7b01069
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