ABCC6 plays a significant role in the transport of nilotinib and dasatinib, and contributes to TKI resistance in vitro, in both cell lines and primary patient mononuclear cells

ATP Binding Cassette family efflux proteins ABCB1 and ABCG2 have previously been demonstrated to interact with Tyrosine Kinase Inhibitors (TKIs); however, evidence for the interaction of other potentially relevant drug transporters with TKIs is lacking. Through Taqman transporter array technology we...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Eadie, Laura N., Dang, Phuong, Goyne, Jarrad M., Hughes, Timothy P., White, Deborah L.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2018
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5792028/
https://ncbi.nlm.nih.gov/pubmed/29385210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0192180
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki