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Gene gating at nuclear pores prevents the formation of R loops

Transcription is an important source of genetic variability. A large amount of transcription-associated genome variation arises from the unscheduled formation of R loops. We have recently found that physical proximity of chromatin to nuclear pores prevents the formation of pathological R loops durin...

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Publicado en:Mol Cell Oncol
Autores principales: Gaillard, Hélène, García-Benítez, Francisco, Aguilera, Andrés
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5791852/
https://ncbi.nlm.nih.gov/pubmed/29404398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2017.1405140
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