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The potential of CRL4DCAF1 and KSR1 as therapeutic targets in merlin-deficient meningioma
BACKGROUND: Merlin-deficient meningiomas are caused by mutations in the Neurofibromin 2 gene and occur in approximately 60% of sporadic meningiomas. Merlin loss is commonly associated with the genetic condition Neurofibromatosis type 2, leading to the development of multiple low grade tumours includ...
Gardado en:
| Publicado en: | Neuro Oncol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5791592/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox238.041 |
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