Type III hypersensitivity reactions to a B cell epitope antigen are abrogated using a depot forming vaccine platform

Peptide antigens are combined with an adjuvant in order to increase immunogenicity in vivo. The immunogenicity and safety of a RSV vaccine formulated in a novel oil-based platform, DepoVax™ (DPX), was compared to an alum formulation. A peptide B cell epitope derived from RSV small hydrophobic ectodo...

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Veröffentlicht in:Hum Vaccin Immunother
Hauptverfasser: MacDonald, Lisa D., MacKay, Alecia, Kaliaperumal, Valarmathy, Weir, Genevieve, Penwell, Andrea, Rajagopalan, Rajkannan, Langley, Joanne M., Halperin, Scott, Mansour, Marc, Stanford, Marianne M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2017
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5791585/
https://ncbi.nlm.nih.gov/pubmed/28933663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21645515.2017.1375637
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