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Detection of Collapse and Crystallization of Saccharide, Protein, and Mannitol Formulations by Optical Fibers in Lyophilization

The collapse temperature (Tc) and the glass transition temperature of freeze-concentrated solutions (Tg') as well as the crystallization behavior of excipients are important physicochemical characteristics which guide the cycle development in freeze-drying. The most frequently used methods to d...

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Bibliografiska uppgifter
I publikationen:Front Chem
Huvudupphovsmän: Horn, Jacqueline, Friess, Wolfgang
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5790775/
https://ncbi.nlm.nih.gov/pubmed/29435445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2018.00004
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