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Use of glass transitions in carbohydrate excipient design for lyophilized protein formulations
This work describes an effort to apply methods from process systems engineering to a pharmaceutical product design problem, with a novel application of statistical approaches to comparing solutions. A computational molecular design framework was employed to design carbohydrate molecules with high gl...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3876287/ https://ncbi.nlm.nih.gov/pubmed/24385675 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.compchemeng.2011.07.018 |
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