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Development of lyophilization cycle and effect of excipients on the stability of catalase during lyophilization

INTRODUCTION: The purpose of the present study was to screen excipients such as amino acids and non-aqueous solvents for their stabilizing effect on catalase, a model protein, for lyophilization. The present study also includes optimization of lyophilization cycle for catalase formulations, which is...

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Detalhes bibliográficos
Main Authors: Lale, Shantanu V, Goyal, Monu, Bansal, Arvind K
Formato: Artigo
Idioma:Inglês
Publicado em: Medknow Publications & Media Pvt Ltd 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3465145/
https://ncbi.nlm.nih.gov/pubmed/23071946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/2230-973X.93007
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