PD-L1 and PD-1 and characterization of tumor-infiltrating lymphocytes in high grade sarcomas of soft tissue – prognostic implications and rationale for immunotherapy

Therapies targeting programmed death 1-(PD-1) or its ligand (PD-L1), promoting antitumor T-cell activity have been successfully introduced into clinical practice. Clinical response correlates with PD-L1 expression by tumor cells or immune cells within the tumor microenvironment. The PD-L1/PD-1 axis...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Boxberg, Melanie, Steiger, Katja, Lenze, Ulrich, Rechl, Hans, von Eisenhart-Rothe, Rüdiger, Wörtler, Klaus, Weichert, Wilko, Langer, Rupert, Specht, Katja
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5790346/
https://ncbi.nlm.nih.gov/pubmed/29399389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1389366
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