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Increased intraepithelial CD3+ T-lymphocytes and high PD-L1 expression on tumor cells are associated with a favorable prognosis in esophageal squamous cell carcinoma and allow prognostic immunogenic subgrouping

Esophageal squamous cell carcinoma (ESCC) is the most common esophageal cancer associated with poor prognosis and additional therapeutic strategies must be implemented to optimize ESCC treatment. Meanwhile, the important biologic role and potential prognostic and therapeutic implications of a tumors...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Jesinghaus, Moritz, Steiger, Katja, Slotta-Huspenina, Julia, Drecoll, Enken, Pfarr, Nicole, Meyer, Petra, Konukiewitz, Björn, Bettstetter, Marcus, Wieczorek, Kathrin, Ott, Katja, Feith, Markus, Langer, Rupert, Weichert, Wilko, Specht, Katja, Boxberg, Melanie
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5564521/
https://ncbi.nlm.nih.gov/pubmed/28657901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.18606
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