Cellular vaccination of MLH1(−/−) mice – an immunotherapeutic proof of concept study

Mismatch-repair deficiency (MMR-D) is closely linked to hypermutation and accordingly, high immunogenicity. MMR-D-related tumors thus constitute ideal vaccination targets for both therapeutic and prophylactic approaches. Herein, the prophylactic and therapeutic impact of a cellular vaccine on tumor...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Maletzki, Claudia, Gladbach, Yvonne Saara, Hamed, Mohamed, Fuellen, Georg, Semmler, Marie-Luise, Stenzel, Jan, Linnebacher, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5790332/
https://ncbi.nlm.nih.gov/pubmed/29399413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1408748
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