Identification of novel leishmanicidal molecules by virtual and biochemical screenings targeting Leishmania eukaryotic translation initiation factor 4A

Leishmaniases are neglected parasitic diseases in spite of the major burden they inflict on public health. The identification of novel drugs and targets constitutes a research priority. For that purpose we used Leishmania infantum initiation factor 4A (LieIF), an essential translation initiation fac...

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Publicado no:PLoS Negl Trop Dis
Main Authors: Harigua-Souiai, Emna, Abdelkrim, Yosser Zina, Bassoumi-Jamoussi, Imen, Zakraoui, Ons, Bouvier, Guillaume, Essafi-Benkhadir, Khadija, Banroques, Josette, Desdouits, Nathan, Munier-Lehmann, Hélène, Barhoumi, Mourad, Tanner, N. Kyle, Nilges, Michael, Blondel, Arnaud, Guizani, Ikram
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5790279/
https://ncbi.nlm.nih.gov/pubmed/29346371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0006160
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