Identification of novel leishmanicidal molecules by virtual and biochemical screenings targeting Leishmania eukaryotic translation initiation factor 4A

Leishmaniases are neglected parasitic diseases in spite of the major burden they inflict on public health. The identification of novel drugs and targets constitutes a research priority. For that purpose we used Leishmania infantum initiation factor 4A (LieIF), an essential translation initiation fac...

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Dades bibliogràfiques
Publicat a:PLoS Negl Trop Dis
Autors principals: Harigua-Souiai, Emna, Abdelkrim, Yosser Zina, Bassoumi-Jamoussi, Imen, Zakraoui, Ons, Bouvier, Guillaume, Essafi-Benkhadir, Khadija, Banroques, Josette, Desdouits, Nathan, Munier-Lehmann, Hélène, Barhoumi, Mourad, Tanner, N. Kyle, Nilges, Michael, Blondel, Arnaud, Guizani, Ikram
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2018
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5790279/
https://ncbi.nlm.nih.gov/pubmed/29346371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0006160
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