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Identification of novel leishmanicidal molecules by virtual and biochemical screenings targeting Leishmania eukaryotic translation initiation factor 4A

Leishmaniases are neglected parasitic diseases in spite of the major burden they inflict on public health. The identification of novel drugs and targets constitutes a research priority. For that purpose we used Leishmania infantum initiation factor 4A (LieIF), an essential translation initiation fac...

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Bibliografske podrobnosti
izdano v:PLoS Negl Trop Dis
Main Authors: Harigua-Souiai, Emna, Abdelkrim, Yosser Zina, Bassoumi-Jamoussi, Imen, Zakraoui, Ons, Bouvier, Guillaume, Essafi-Benkhadir, Khadija, Banroques, Josette, Desdouits, Nathan, Munier-Lehmann, Hélène, Barhoumi, Mourad, Tanner, N. Kyle, Nilges, Michael, Blondel, Arnaud, Guizani, Ikram
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5790279/
https://ncbi.nlm.nih.gov/pubmed/29346371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0006160
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