Probability of phenotypically detectable protein damage by ENU-induced mutations in the Mutagenetix database

Computational inference of mutation effects is necessary for genetic studies in which many mutations must be considered as etiologic candidates. Programs such as PolyPhen-2 predict the relative severity of damage caused by missense mutations, but not the actual probability that a mutation will reduc...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Wang, Tao, Bu, Chun Hui, Hildebrand, Sara, Jia, Gaoxiang, Siggs, Owen M., Lyon, Stephen, Pratt, David, Scott, Lindsay, Russell, Jamie, Ludwig, Sara, Murray, Anne R., Moresco, Eva Marie Y., Beutler, Bruce
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5789985/
https://ncbi.nlm.nih.gov/pubmed/29382827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-02806-4
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados