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X-linked cholestasis in mouse due to mutations of the P4-ATPase ATP11C

Transporters at the hepatic canalicular membrane are essential for the formation of bile and the prevention of cholestatic liver disease. One such example is ATP8B1, a P4-type ATPase disrupted in three inherited forms of intrahepatic cholestasis. Mutation of the X-linked mouse gene Atp11c, which enc...

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Detalhes bibliográficos
Main Authors: Siggs, Owen M., Schnabl, Bernd, Webb, Bill, Beutler, Bruce
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3093471/
https://ncbi.nlm.nih.gov/pubmed/21518881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1104631108
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