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ZBTB1 is a determinant of lymphoid development

In this study, we describe a chemically induced mouse mutation that caused a complete and cell-intrinsic T cell deficiency. Development of other lymphoid lineages was also partially impaired and was severely compromised under competitive conditions. Positional cloning, retroviral transduction, and a...

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Detalhes bibliográficos
Main Authors: Siggs, Owen M., Li, Xiaohong, Xia, Yu, Beutler, Bruce
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3260866/
https://ncbi.nlm.nih.gov/pubmed/22201126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20112084
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