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Nominal carbonic anhydrase activity minimizes airway‐surface liquid pH changes during breathing

The airway‐surface liquid pH (pH(ASL)) is slightly acidic relative to the plasma and becomes more acidic in airway diseases, leading to impaired host defense. CO (2) in the large airways decreases during inspiration (0.04% CO (2)) and increases during expiration (5% CO (2)). Thus, we hypothesized th...

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Bibliografske podrobnosti
izdano v:Physiol Rep
Main Authors: Thornell, Ian M., Li, Xiaopeng, Tang, Xiao Xiao, Brommel, Christian M., Karp, Philip H., Welsh, Michael J., Zabner, Joseph
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5789725/
https://ncbi.nlm.nih.gov/pubmed/29380953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.13569
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