Nominal carbonic anhydrase activity minimizes airway‐surface liquid pH changes during breathing

The airway‐surface liquid pH (pH(ASL)) is slightly acidic relative to the plasma and becomes more acidic in airway diseases, leading to impaired host defense. CO (2) in the large airways decreases during inspiration (0.04% CO (2)) and increases during expiration (5% CO (2)). Thus, we hypothesized th...

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Detaylı Bibliyografya
Yayımlandı:Physiol Rep
Asıl Yazarlar: Thornell, Ian M., Li, Xiaopeng, Tang, Xiao Xiao, Brommel, Christian M., Karp, Philip H., Welsh, Michael J., Zabner, Joseph
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2018
Konular:
Original Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5789725/
https://ncbi.nlm.nih.gov/pubmed/29380953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.13569
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