A Reproducibility-Based Computational Framework Identifies an Inducible, Enhanced Antiviral State in Dendritic Cells from HIV-1 Elite Controllers

BACKGROUND: Human immunity relies on the coordinated responses of many cellular subsets and functional states. Inter-individual variations in cellular composition and communication could thus potentially alter host protection. Here, we explore this hypothesis by applying single-cell RNA-sequencing t...

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Gepubliceerd in:Genome Biol
Hoofdauteurs: Martin-Gayo, Enrique, Cole, Michael B., Kolb, Kellie E., Ouyang, Zhengyu, Cronin, Jacqueline, Kazer, Samuel W., Ordovas-Montanes, Jose, Lichterfeld, Mathias, Walker, Bruce D., Yosef, Nir, Shalek, Alex K., Yu, Xu G.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2018
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Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5789701/
https://ncbi.nlm.nih.gov/pubmed/29378643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-017-1385-x
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