Cardiac macrophages promote diastolic dysfunction

Macrophages populate the healthy myocardium and, depending on their phenotype, may contribute to tissue homeostasis or disease. Their origin and role in diastolic dysfunction, a hallmark of cardiac aging and heart failure with preserved ejection fraction, remain unclear. Here we show that cardiac ma...

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Detalles Bibliográficos
Publicado en:J Exp Med
Main Authors: Hulsmans, Maarten, Sager, Hendrik B., Roh, Jason D., Valero-Muñoz, María, Houstis, Nicholas E., Iwamoto, Yoshiko, Sun, Yuan, Wilson, Richard M., Wojtkiewicz, Gregory, Tricot, Benoit, Osborne, Michael T., Hung, Judy, Vinegoni, Claudio, Naxerova, Kamila, Sosnovik, David E., Zile, Michael R., Bradshaw, Amy D., Liao, Ronglih, Tawakol, Ahmed, Weissleder, Ralph, Rosenzweig, Anthony, Swirski, Filip K., Sam, Flora, Nahrendorf, Matthias
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2018
Assuntos:
Research Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5789416/
https://ncbi.nlm.nih.gov/pubmed/29339450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20171274
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