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Involvement of the ubiquitin-proteasome system in the expression of extracellular matrix genes in retinal pigment epithelial cells

Emerging evidence suggests that dysfunction of the ubiquitin-proteasome system is involved in the pathogenesis of numerous senile degenerative diseases including retinal disorders. The aim of this study was to assess whether there is a link between proteasome regulation and retinal pigment epitheliu...

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Dettagli Bibliografici
Pubblicato in:Biochem Biophys Rep
Autori principali: Ramos de Carvalho, J. Emanuel, Verwoert, Milan T., Vogels, Ilse M.C., Reits, Eric A., Van Noorden, Cornelis J.F., Klaassen, Ingeborg, Schlingemann, Reinier O.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5789218/
https://ncbi.nlm.nih.gov/pubmed/29387813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2018.01.005
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