Spatiotemporal patterning of EpCAM is important for murine embryonic endo- and mesodermal differentiation

Epithelial cell adhesion molecule EpCAM is expressed in pluripotent embryonic stem cells (ESC) in vitro, but is repressed in differentiated cells, except epithelia and carcinomas. Molecular functions of EpCAM, possibly imposing such repression, were primarily studied in malignant cells and might not...

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Опубликовано в: :Sci Rep
Главные авторы: Sarrach, Sannia, Huang, Yuanchi, Niedermeyer, Sebastian, Hachmeister, Matthias, Fischer, Laura, Gille, Sebastian, Pan, Min, Mack, Brigitte, Kranz, Gisela, Libl, Darko, Merl-Pham, Juliane, Hauck, Stefanie M., Paoluzzi Tomada, Elisa, Kieslinger, Matthias, Jeremias, Irmela, Scialdone, Antonio, Gires, Olivier
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2018
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5789065/
https://ncbi.nlm.nih.gov/pubmed/29379062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-20131-8
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