Spatiotemporal patterning of EpCAM is important for murine embryonic endo- and mesodermal differentiation

Epithelial cell adhesion molecule EpCAM is expressed in pluripotent embryonic stem cells (ESC) in vitro, but is repressed in differentiated cells, except epithelia and carcinomas. Molecular functions of EpCAM, possibly imposing such repression, were primarily studied in malignant cells and might not...

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Publicado en:Sci Rep
Main Authors: Sarrach, Sannia, Huang, Yuanchi, Niedermeyer, Sebastian, Hachmeister, Matthias, Fischer, Laura, Gille, Sebastian, Pan, Min, Mack, Brigitte, Kranz, Gisela, Libl, Darko, Merl-Pham, Juliane, Hauck, Stefanie M., Paoluzzi Tomada, Elisa, Kieslinger, Matthias, Jeremias, Irmela, Scialdone, Antonio, Gires, Olivier
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2018
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5789065/
https://ncbi.nlm.nih.gov/pubmed/29379062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-20131-8
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