Regulation of autophagy, mitochondrial dynamics, and cellular bioenergetics by 4-hydroxynonenal in primary neurons

The production of reactive species contributes to the age-dependent accumulation of dysfunctional mitochondria and protein aggregates, all of which are associated with neurodegeneration. A putative mediator of these effects is the lipid peroxidation product 4-hydroxynonenal (4-HNE), which has been s...

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Dettagli Bibliografici
Pubblicato in:Autophagy
Autori principali: Dodson, Matthew, Wani, Willayat Y., Redmann, Matthew, Benavides, Gloria A., Johnson, Michelle S., Ouyang, Xiaosen, Cofield, Stacey S., Mitra, Kasturi, Darley-Usmar, Victor, Zhang, Jianhua
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2017
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5788494/
https://ncbi.nlm.nih.gov/pubmed/28837411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2017.1356948
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