TET1 deficiency attenuates the DNA damage response and promotes resistance to DNA damaging agents

Recent studies have shown that loss of TET1 may play a significant role in the formation of tumors. Because genomic instability is a hallmark of cancer, we examined the potential involvement of 10-11 translocation 1 (TET1) in the DNA damage response (DDR). Here we demonstrate that, in response to cl...

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Detalhes bibliográficos
Publicado no:Epigenetics
Main Authors: Coulter, Jonathan B., Lopez-Bertoni, Hernando, Kuhns, Katherine J., Lee, Richard S., Laterra, John, Bressler, Joseph P.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5788409/
https://ncbi.nlm.nih.gov/pubmed/28758831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2017.1359452
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